Max More Speaks Out on Cryonics and Transhumanism

Max More: Cryonics and the Morality of Progress
If you would like to support this podcast, click here. Max More is an author, philosopher, futurist and former CEO of Alcor Life Extension Foundation. He is the Director of Communications for Biostasis Technology. Max was the author of the first modern definition of \”Transhumanism\”.

来源和详细信息:
https://arjunkhemani.substack.com/p/24-max-more-cryonics-transhumanism

New Drug-Like Molecule (MIC) Extends Lifespan and Enhances Mitochondrial Function

A new drug-like molecule increases lifespan in worms, improves pathology and enhances function in mammalian muscles cells

Healthy mitochondria are the organelles in our cells that produce energy. This is true for humans as well as C. elegans (a small, short-lived, nematode used to study aging).

Researchers at Buck Institute identified a new druglike molecule which keeps mitochondria healthy through mitophagy. Mitophagy is a process in which damaged mitochondria are removed and recycled by multicellular organisms. The compound MIC is a natural substance that has extended the lifespan of C. elegans and ameliorated neurodegenerative disease in C. elegans models. It also improved mitochondrial function within mouse muscle cells. The results will be published in Nature Aging’s November 13th, 2023 edition.

A defect in mitophagy may be responsible for many age-related illnesses. It is linked to neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and heart failure. It also influences metabolic disorders like obesity and type 2 diabetics.

来源和详细信息:
https://medicalxpress.com/news/2023-11-drug-like-molecule-lifespan-ameliorates-pathology.html

Discovering the Powerful Mitophagy-Inducing Compound (MIC) to Promote Healthier Mitochondria

New molecule promoting healthy mitochondria via mitophagy found

Mitophagy inducing compound (MIC), a naturally occurring compound found in plants, can help combat age-related illnesses by promoting mitochondrial function through mitophagy.

Mohammed Haneefa Nizamudeen / iStock.

Scientists have stated that mitophagy involves the removal and recycling of damaged mitochondria from multicellular organisms.

来源和详细信息:
https://interestingengineering.com/health/new-molecule-promotes-healthy-mitochondria

Conquer Aging or Die Trying Podcast Episode 1: Crissman Loomis (@UnAging.com) – Exclusive Discount Links and Join our Patreon Campaign!

Conquer Aging or Die Trying Podcast, Episode #1: Crissman Loomis (@Unaging.com)
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Synthetic ‘Super Melanin” Cream Effective in Treating Sunburn and Chemical Burns

Super Melanin heals skin injuries from sunburns, chemical burns

Imagine a cream that can heal skin damage caused by environmental toxins or sunlight. Scientists at Northwestern University have developed a biomimetic, synthetic melanin that could be used to heal skin damage.

In a recent study, scientists have shown that their synthetic, melanin mimicking the melanin found in the human skin can be applied topically on injured skin to accelerate wound healing. These effects are seen both on the skin and throughout the body.

Scientists said that when applied as a cream, synthetic melanin protects the skin from the sun and heals the skin damaged by sun damage or chemical burning. The technology works by scavenging the free radicals that are produced when skin is injured, such as by sunburn. Unchecked free radical activity can damage cells, resulting in skin cancer and aging.

来源和详细信息:

‘Super Melanin’ Heals Skin Injuries from Sunburn, Chemical Burns

Fortune Magazine provided details about a rigorous daily regimen followed by a 45-year-old CEO, who spent millions every year to rejuvenate. From diet and exercise, he went all-out in his attempt to revive himself.

Bryan Johnson explains his daily routine to Fortune Magazine in Spanish
Bryan Johnson’s daily routine Cortesy Fortune Magazine

The video was first published in Fortune Magazine, March 27, 2023.

The article’s title is \”The strict antiaging routine of 45-year old CEO who spends millions per year to look 18 again – from diet to exercise\”.

You can read the entire article by clicking here: https://fortune.com/well/2023/03/19/bryan-johnson-anti-aging…-exercise/

来源和详细信息:

Discovery of Bacterial Protein with Potential to Treat Mitochondrial Dysfunction

A study reveals that a bacterial protein can keep human cells healthy

Researchers from the University of Sao Paulo in Brazil have discovered a novel protein produced by bacteria that is capable of keeping human cells healthy, even when they are under a heavy burden of bacteria. This discovery could lead new treatments for many diseases related to mitochondrial dysfunction such as cancers and auto-immune conditions. Mitochondria, which are organelles in cells that provide most of the energy for biochemical reactions within cells, are the source of this chemical energy.

The study was published in PNAS. Researchers analyzed 130 of the proteins that Coxiella burnetii releases when it invades host cells. They found at least one protein capable of prolonging cellular longevity by directly acting on mitochondria.

C. burnetii, after invading the host cell, releases a protein that was previously unknown, called mitochondrial coxiella-effector F (MceF) by the authors. MceF interacts glutathione-peroxidase 4(GPX4) an antioxidant enzyme found in mitochondria to improve mitochondrial functions by promoting anti-oxidizing effects that prevent cell damage and death.

来源和详细信息:
https://phys.org/news/2023-11-reveals-bacterial-protein-capable-human.html