Reduce Isoleucine Intake for Improved Longevity in Mice

Cutting back on one amino acid increases the life expectancy of middle-aged mice by up to 33%

In a new study, mice were given a limited amount of an essential amino acid that slowed down the effects of aging and extended their life span.

Scientists wonder if this research could improve longevity and quality-of-life.

Isoleucine, one of the three branched chain amino acids that we use in our body to make proteins, is one of these. Since our cells cannot produce it, we must get it through sources such as eggs, dairy products, soy proteins, and meats.

来源和详细信息:
https://www.sciencealert.com/cutting-back-on-one-amino-acid-increases-lifespan-of-middle-aged-mice-up-to-33

Uncovering the Role of CD300f as an Essential Protein in Supporting Aging Well

A study identifies the key protein to healthy aging

A study published in Cell Reports found that a protein in certain immune cells can determine the life expectancy of mice and the healthy aging process. This protein, also known as the CD300f immuno receptor, is absent in animal models, which results in a reduced life expectancy, cognitive decline, and premature aging.

Hugo Peluffo is the leader of the study and a member of the Faculty of Medicine and Health Sciences and Institute of Neurosciences at the University of Barcelona.

Understanding the role of CD300f, the immune receptor, in determining the rate at which aging-associated diseases manifest, will help us better understand the process and contribute to designing strategies that regulate it. The expert notes that \”the immune receptor CD300f can be used as a biomedical target.\” Our team has also shown previously that some variants CD300f of the immune receptor may be useful in patients as biomarkers.

来源和详细信息:
https://medicalxpress.com/news/2023-11-key-protein-healthy-aging.html

Impact of Epigenetic Age on Cognitive Function and Memory Performance

Memory and cognitive function are affected by epigenetic age acceleration

According to new research, biological age as determined by DNA methylation has a greater impact on cognitive abilities such as memory and processing speed. This discovery could change our understanding of cognitive health and aging.

来源和详细信息:
https://www.psypost.org/2023/11/epigenetic-age-acceleration-linked-to-poorer-memory-performance-and-cognitive-functioning-214743

Can Taurine Reverse Aging in Humans?

Taurine seems to reverse the aging process in animals. Can it work the same way for us?
Taurine, an energy drink micronutrient, is one of the ingredients that may help you live longer and healthier.

Taurine was found to increase longevity in animals.

来源和详细信息:
https://www.freethink.com/health/taurine-longevity

Breakthrough in 3D-Printed Skin Grafts: Scientists Unleash Hair Follicles for Growth.

Scientists 3D Print Hair Follicles on Lab-Grown Skin

This technique is a significant step forward in the development of skin grafts and drug testing. Scientists at Rensselaer Polytechnic Institute have 3D printed hair follicles on human skin tissue in the laboratory. It is the first time that researchers have used this technology to create hair follicles. Hair follicles play a key role in skin healing.

The findings, published in Science Advances journal, could have applications in regenerative medicines and drug testing. However, it will be several years before engineers can create skin grafts with hair.

Our work is a proof of concept that 3D-bioprinting can create hair follicles in a reproducible, highly accurate way. The study was led by Pankaj Karande Ph.D. an associate professor in chemical and biological engineering and member of the Shirley Ann Jackson Ph.D. Center for Biotechnology and Interdisciplinary Studies at Rensselaer.

来源和详细信息:

Scientists 3D-Print Hair Follicles in Lab-Grown Skin

Millionaire Experiment to Reverse Aging Through Science

The man who spends millions on aging?
Bryan Johnson, 45 years old, uses his life to test how long he will live, and to try to reverse the signs of aging. NBC News’ Gadi Schwartz reports.

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来源和详细信息:

Serratia marcescens Is a Recurring Problem in Oral Microbiome Tests #8 and 9

Serratia marcescens is still a problem in the oral microbiome tests #8 and 9.
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来源和详细信息:
https://www.youtube.com/watch?v=DkOceKds2a8