Alzheimer’s Disease: Proteins can predict signs and symptoms
Cross-sectional proteomic analysis showed that markers of Alzheimer’s and neurodegeneration were associated with protein indicators of subclinical health in plasma.
Researchers at the National Institute on Aging, Baltimore, found that higher levels of plasma biomarkers for amyloid beta, phosphorylated Tau181 (ptau181) and neurofilament (NfL), a measure neuronal damage, and glial fibrillary acidsic protein (GFAP), a measure astrogliosis, were associated with a greater risk of cardiovascular disease and heart failure mortality.
Walker and co-authors in Annals of Neurology found that ptau181, NfL and GFAP were also related to proteomic indicators of lean body mass and visceral fatty tissue.
来源和详细信息：
https://www.medpagetoday.com/neurology/dementia/107467