先须挽取银河水，后方栽种太华山
衰老进化和寿命的最新进展
衰老过程在生物体中很常见。 然而，不同物种的脊椎动物的寿命差异很大。 DNA 损伤的逐渐增加、细胞器的破坏、蛋白质功能失调、新陈代谢紊乱和氧化应激都是导致衰老的因素。
长寿。 技术：寿命的差异是由生物体基因组的进化路径和权衡所驱动的。 特定年龄的选择也会影响人群中等位基因（基因变异）的频率。 环境将影响死亡风险以及疾病易感性。 细胞的生命史及其年龄也会影响体细胞和种系组织的突变过程。
《遗传学趋势》中的一篇新评论探讨了人口、有机体和细胞水平上衰老的进化和生物学的最新进展。
来源和详细信息：
富含因果关系的表观遗传年龄将适应和损害分开
他们使用孟德尔随机化方法识别出因果丰富且与衰老相关的 CpG。 他们开发了新的表观遗传时钟 – DamAge 和 AdaptAge – 可以更准确地跟踪与年龄相关的变化，从而提供对衰老机制的见解。
来源和详细信息：
https://www.nature.com/articles/s43587-023-00557-0
Why I am not afraid of death
Here is a video of a deathist. Cool guy, this fellow runs a great channel. He seems to believe that a longer life will make you less motivated, and only death’s knowledge can motivate you. I left a comment.
来源和详细信息：
The Tech Breakthrough that is Bringing Us Closer To Immortality
It’s not what we thought it would be.
来源和详细信息：
https://www.popularmechanics.com/science/a46330487/immortality-breakthrough/
Alzheimer’s Disease and Focused Ultrasound Delivery
This article is part of an ongoing series about the latest developments in Regenerative Medicine. This article discusses the latest advances in Alzheimer’s treatment.
In 1999, I defined the term regenerative medicine to include a collection of interventions designed to restore normal function in tissues and organs that have been damaged by disease or trauma. I include the full spectrum of cell-based therapies and biomechanical interventions, as well as chemical, gene and protein-based medicine.
A combination of focused ultrasonic therapy and a medication recently approved could be the best treatment we have for Alzheimer’s to date. In the New England Journal of Medicine Dr. Ali Rezai, along with colleagues from West Virginia University, describe a method to reduce cerebral amyloid beta load, a neurodegeneration biomarker, in Alzheimer’s patients. Although still in its early stages, this combination treatment could help millions of people suffering from Alzheimer’s disease in the future.
来源和详细信息：
https://www.forbes.com/sites/williamhaseltine/2024/01/19/combating-alzheimers-with-focused-ultrasound-drug-delivery/?sh=54f60219c56d
New plant cell discoveries promise human anti-aging benefits
Researchers make a new discovery that could hold the key to slowing down plant aging. Find out what it means for the future by clicking here.
来源和详细信息：
https://interestingengineering.com/science/a-new-plant-cell-discovery-promises-human-anti-aging-potential
Trigonelline Increases NAD, Improves Muscle Function, And Extends Lifespan: Vincenzo Sorrentino, PhD
Join us on Patreon. https://www.patreon.com/MichaelLustgartenPhDDiscount Links: Telomere, Epigenetic Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7x…
来源和详细信息：
You don’t need to be concerned about your life expectancy. Your health span is what you should be concerned about.
Researchers are increasingly focused on finding out how to live longer and disease-free.
来源和详细信息：
https://www.nationalgeographic.com/premium/article/live-better-longer-healthspan?cmpid=org=ngp::mc=social::src=facebook::cmp=editorial::add=fb20240121science-healthspan&linkId=279989624