先须挽取银河水，后方栽种太华山
The development of a life-extension drug for big dogs is getting closer to reality
FDA has not yet approved any drug for life extension. Loyal Biotech is one step closer to getting a drug approved for dogs.
来源和详细信息：
https://www.wired.com/story/a-life-extension-drug-for-big-dogs-is-getting-closer-to-reality/
Triglycerides with Longevity
Join us on Patreon. https://www.patreon.com/MichaelLustgartenPhD
Discount Links
At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten.
Use code: CONQUERAGING at Checkout.
Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ6…M0&irgwc=1
Use code: CONQUERAGING
NAD+ Quantification: https://www.jinfiniti.com/product/intracellular-nad-test/
Use code: ConquerAging at Checkout.
Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten.
Enter code: ConquerAging
At-Home Blood Testing (SiPhox Health): https://getquantify.io/mlustgarten.
来源和详细信息：
Biking can help improve healthspan.
High-intensity Interval Training (HIIT) is becoming increasingly popular. It involves alternating periods of intense, anaerobic activity with periods of recovery. The goal is to reduce body fat, improve strength and endurance and increase healthspan.
Even finding 30 minutes can be difficult these days. Enter CAROL Bike. This exercise bike is designed with Reduced Exertion High Intensity Interval Training (REHIT), and AI-personalization. It allows for a 5-minute workout that’s effective.
Longevity. CAROL Bike was developed in collaboration with leading researchers to improve fitness and reduce blood pressure. It also decreases diabetes risk. We were interested in CAROL Bike because it was based on scientific studies and not just \”feel the burn\” or \”if it hurts it must work\”. Ulrich Dempfle is the co-founder and CEO of CAROL Bike. He used his mechanical engineering background to create the world’s first Reduced Exertion High Intensity Interval Training (REHIT).
来源和详细信息：
Improving healthspan and longevity can be just like riding a bike
The FDA is getting closer to approving a new drug that could extend the lives of dogs
If it is a quality of life, then yes. You could even use this example to help humans live longer.
The FDA has for the first time indicated that it is willing to endorse a drug that promotes longevity.
来源和详细信息：
https://www.smithsonianmag.com/smart-news/a-new-drug-that-could-extend-dogs-lives-inches-closer-to-approval-180983331/
Can a drug give your pet more dog years?
The development of longevity drugs for canine companions is gaining momentum. The question of what success might look like is also raised.
来源和详细信息：
https://www.nytimes.com/2023/11/28/science/longevity-drugs-dogs.html
Cutting back on one amino acid increases the life expectancy of middle-aged mice by up to 33%
In a new study, mice were given a limited amount of an essential amino acid that slowed down the effects of aging and extended their life span.
Scientists wonder if this research could improve longevity and quality-of-life.
Isoleucine, one of the three branched chain amino acids that we use in our body to make proteins, is one of these. Since our cells cannot produce it, we must get it through sources such as eggs, dairy products, soy proteins, and meats.
来源和详细信息：
https://www.sciencealert.com/cutting-back-on-one-amino-acid-increases-lifespan-of-middle-aged-mice-up-to-33
A study identifies the key protein to healthy aging
A study published in Cell Reports found that a protein in certain immune cells can determine the life expectancy of mice and the healthy aging process. This protein, also known as the CD300f immuno receptor, is absent in animal models, which results in a reduced life expectancy, cognitive decline, and premature aging.
Hugo Peluffo is the leader of the study and a member of the Faculty of Medicine and Health Sciences and Institute of Neurosciences at the University of Barcelona.
Understanding the role of CD300f, the immune receptor, in determining the rate at which aging-associated diseases manifest, will help us better understand the process and contribute to designing strategies that regulate it. The expert notes that \”the immune receptor CD300f can be used as a biomedical target.\” Our team has also shown previously that some variants CD300f of the immune receptor may be useful in patients as biomarkers.
来源和详细信息：
https://medicalxpress.com/news/2023-11-key-protein-healthy-aging.html
Memory and cognitive function are affected by epigenetic age acceleration
According to new research, biological age as determined by DNA methylation has a greater impact on cognitive abilities such as memory and processing speed. This discovery could change our understanding of cognitive health and aging.
来源和详细信息：
https://www.psypost.org/2023/11/epigenetic-age-acceleration-linked-to-poorer-memory-performance-and-cognitive-functioning-214743