先须挽取银河水，后方栽种太华山
Bryan Johnson explains his daily routine to Fortune Magazine in Spanish
Bryan Johnson’s daily routine Cortesy Fortune Magazine
The video was first published in Fortune Magazine, March 27, 2023.
The article’s title is \”The strict antiaging routine of 45-year old CEO who spends millions per year to look 18 again – from diet to exercise\”.
You can read the entire article by clicking here: https://fortune.com/well/2023/03/19/bryan-johnson-anti-aging…-exercise/
来源和详细信息：
How long can humans survive? #longevity #healthspan #lifespan
来源和详细信息：
A study reveals that a bacterial protein can keep human cells healthy
Researchers from the University of Sao Paulo in Brazil have discovered a novel protein produced by bacteria that is capable of keeping human cells healthy, even when they are under a heavy burden of bacteria. This discovery could lead new treatments for many diseases related to mitochondrial dysfunction such as cancers and auto-immune conditions. Mitochondria, which are organelles in cells that provide most of the energy for biochemical reactions within cells, are the source of this chemical energy.
The study was published in PNAS. Researchers analyzed 130 of the proteins that Coxiella burnetii releases when it invades host cells. They found at least one protein capable of prolonging cellular longevity by directly acting on mitochondria.
C. burnetii, after invading the host cell, releases a protein that was previously unknown, called mitochondrial coxiella-effector F (MceF) by the authors. MceF interacts glutathione-peroxidase 4(GPX4) an antioxidant enzyme found in mitochondria to improve mitochondrial functions by promoting anti-oxidizing effects that prevent cell damage and death.
来源和详细信息：
https://phys.org/news/2023-11-reveals-bacterial-protein-capable-human.html
Let’s all get better at playing don’t Die every day.
Bryan Johnson, the most famous biohacker in the world and possibly the \”most measured person in human history\”, is a man of many talents. Bryan Johnson is on a quest to reverse the biological age of all 70 of his organs to extend his life and improve his health. He will then share his protocol to allow others to benefit from his research, experience and experiments.
Johnson’s philosophy can be summarized as \”don’t die.\” To that end, his book or novel entitled Don’t Die is available as a free eBook from his website. The uncorrected version of the advanced reading edition is also available. Johnson’s pseudonym for this project is Zero. He describes himself as \”the first individual H. sapiens who has exceeded five hundred years old,\” and dies in 2 478 by accident rather than through old age. This leaves him just weeks from becoming \”Homo Deus.\” Johnson also credits Zero with inventing Zeroism, the resurrection technology undie and fathering \”millions\” of biological and digital descendants who live \”in the far reaches and beyond the solar system.\”
Longevity. Technology: Since Don’t Die was written as a novel, Johnson could explore his philosophy a little differently. He invited us to watch the narrator Scribe on his final day on Earth. As he muses about humanity’s evolution in the future, the nature and impact of free will, and age reversal, and programmable biological. Scribe is joined in the story by characters from Pilgrim’s Progress, such as Cognitive Bias and Dark Humor, Game Play, and Self Critical.
来源和详细信息：
‘We all play don’t die every day – now let’s get really, really good at it’
复兴创业峰会公布首批发言人
由 Forever Healthy 基金会主办的复兴峰会（柏林，2024 年 5 月 10 日至 11 日）是一场热闹的社交活动，旨在加速复兴生物技术的发展。
返老还童/长寿生物技术是一个新兴的医学领域。 它的目的是通过攻击其根源——衰老过程来预防和逆转衰老疾病。 年轻化疗法旨在逆转或修复与年龄相关的细胞变化，例如分子毒素、钙化、组织僵硬、基因突变和能量受损。
来源和详细信息：
这种蛋白质可以通过阻断来增强肌肉
斯坦福大学的研究人员发现，阻断单一蛋白质的疗法可以逆转小鼠与年龄相关的肌肉损失。 这一发现表明，老年人可能不是唯一受益于这种治疗的人。
与年龄相关的肌肉损失。 人们在30多岁时开始失去肌肉质量。 到 50 岁时，他们每十年可能会损失 10% 的肌肉质量。
通过锻炼可以恢复失去的肌肉。 然而，某些健康状况可能会造成困难。 然而，未解决与年龄相关的肌肉损失可能会导致活动能力下降和虚弱。 这会增加跌倒或其他伤害的风险。
来源和详细信息：
https://www.freethink.com/health/age-related-muscle-loss
犬尿氨酸/色氨酸比率：许多促炎和抗炎因素的综合测量
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折扣链接
家庭代谢组学：https://www.iollo.com?ref=michael-lustgarten。
结帐时使用代码：CONQUERAGING。
NAD+ 定量：https://www.jinfiniti.com/product/intracellular-nad-test/
结帐时使用代码：ConquerAging。
表观遗传、端粒测试：https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ6…M0&irgwc=1
使用代码：征服
口腔微生物组：https://www.bristlehealth.com/?ref=michaellustgarten。
输入代码：征服衰老
家庭血液检测 (SiPhox Health)：https://getquantify.io/mlustgarten。
来源和详细信息：
阻断导致肌肉无力的酶是可能的。
斯坦福大学医学院的干细胞生物学家 Helen Blau 和她的同事发现，经过一个月的治疗，阻断 15 PGDH 可以恢复老年小鼠的肌肉并增强其力量。 相比之下，在幼鼠体内增加15-PGDH水平一个月后，它们的肌肉质量下降，变得越来越虚弱。
Blau 的研究小组发现，随着肌纤维和运动神经细胞之间的通讯联系丧失，15-PGDH 会在肌肉中积聚。 这是衰老的另一个影响。 研究小组在《科学转化医学》杂志上报告说，用抑制 15-PGDH 的药物治疗老年小鼠一个月，可以恢复肌肉纤维、运动神经细胞和连接之间的突触。 它还增加了动物的力量。 这些突触使大脑能够指挥肌肉。
根据研究结果，阻断 gerozyme-15-PGDH 可以帮助恢复因神经损伤、运动神经细胞疾病或衰老而损失的力量。
来源和详细信息：
Blocking an aging-related enzyme may restore muscle strength