月度归档： 2024 年 3 月

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人体细胞为新型伤口愈合机器人提供动力

治愈伤口的微型机器人仅由一个人体细胞制成
科学家们可能刚刚为再生医学的武器库添加了一种新武器：由活体人类细胞制成的微型生物机器人。 自组装机器人虽然很小，但功能却很强大。 一项研究表明，它们治愈和治疗疾病的潜力巨大。

2020 年，该团队通过利用青蛙细胞创建 Xenobots 展示了他们在生物机器人领域的专业知识。 该团队甚至设计了异种机器人，使其能够以其他生物体或植物无法做到的方式进行繁殖，这是以前从未做过的事情。

研究人员不确定异种机器人令人难以置信的能力是否可以归因于它们的两栖起源。 他们想看看是否可以用其他生物体的细胞制造生物机器人。 为什么不从人类开始呢？

来源和详细信息：
https://www.iflscience.com/these-tiny-wound-healing-robots-start-life-as-just-1-human-cell-71808

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利美尼定：一种延缓衰老、延长寿命的高血压药物

服用普通降压药的动物寿命更长、衰老速度更慢

对于蠕虫来说，高血压药物利美尼定可以延缓衰老。 从理论上讲，这种效应可能对人类晚年有益。

在之前的研究中，利美尼定被证明可以模拟热量限制对细胞水平的影响。 在动物模型中，已经证明在保持营养的同时减少能量摄入可以延长预期寿命。

关于这是否适用于人类生物学或对我们的健康构成风险的争论仍在继续。 寻找在不极度减少热量的情况下改善老年健康的新方法可能是获得相同益处的关键。

来源和详细信息：
https://www.sciencealert.com/common-blood-pressure-drug-increases-lifespan-slows-aging-in-animals

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The X Prize: A $101 Million Quest to Reverse Aging and Improve Health

With a new award of $101 million, the X Prize takes aim at aging

The top prize will go to the team that restores at least 10 years of muscle, immune, and brain function in older adults.

Money cannot buy happiness but X Prize’s founder Peter Diamandis believes it could buy better health.

来源和详细信息：
https://www.technologyreview.com/2023/11/29/1084052/x-prize-aging-101-million-award/

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Anthrobots: Harnessing Nanobiobots for Neuroregeneration

Anthrobots: Tiny biobots from human cells heal neurons

Summary: Researchers have developed microscopic biological robots called ‘Anthrobots’ made from human tracheal cell. They show potential for healing and regenerative medicines.

The self-assembling robots are available in sizes ranging from a hair’s width to a pencil-point. They show remarkable healing effects in laboratory conditions, especially in the growth of neuron cells across damaged areas.

This study, based on Xenobot research from earlier, reveals that Anthrobots are created using adult human cells, without genetic modification. It offers a new way to create patient-specific therapeutic instruments.

来源和详细信息：

Anthrobots: Tiny Biobots From Human Cells Heal Neurons

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The $101 Million XPrize Challenge: Reversing Aging and Expanding Healthspans

The New XPrize Award Will Provide $101 Million to Innovators who Can Reverse Aging

The contest is designed to encourage innovation in the field of ‘longer healthspans’ by promoting treatments that reverse age-related degenerations of body, mind, and immune system.

来源和详细信息：
https://www.forbes.com/sites/alexknapp/2023/11/29/new-xprize-will-award-101-million-to-innovators-who-can-reverse-aging/

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Dinosaur Dominance: How Ancient Reptiles Influenced Human Aging

Researchers suggest that dinosaurs could have had an influence on how humans age.

Science: Recent research suggests that dinosaurs could have had an influence on how humans age.

According to a new hypothesis from a leading expert on aging, millions of years dinosaur dominance may have influenced human aging. Professor Joao de Magalhaes of the University of Birmingham has proposed the ‘longevity-bottleneck’ hypothesis in a recent study published in BioEssays. The hypothesis relates the role dinosaurs played in the past 100 million years to the aging of mammals.

All mammals, including humans, show a distinct aging process.

The hypothesis of Professor de Magalhaes suggests that, during the Mesozoic Period, during the reigning dinosaurs, mammals were under constant pressure to reproduce rapidly, and this over a period of 100 million years resulted in the loss or deactivation of genes related to long life. These include processes linked with DNA repair, tissue regeneration, and the ability to regenerate tissues.

来源和详细信息：
https://phys.org/news/2023-11-longevity-bottleneck-hypothesis-dinosaurs-human.html