斯坦福大学医学院研究预测哪个器官将首先衰竭
斯坦福大学医学院的科学家们领导了一项新的研究,展示了一种通过分析血液中不同蛋白质或蛋白质组来研究器官衰老的简单方法。 这使得可以预测个人患病的风险。
来源和详细信息:
https://med.stanford.edu/news/all-news/2023/12/aging-organs.html
先须挽取银河水,后方栽种太华山
斯坦福大学医学院研究预测哪个器官将首先衰竭
斯坦福大学医学院的科学家们领导了一项新的研究,展示了一种通过分析血液中不同蛋白质或蛋白质组来研究器官衰老的简单方法。 这使得可以预测个人患病的风险。
来源和详细信息:
https://med.stanford.edu/news/all-news/2023/12/aging-organs.html
永生与数字死亡的局限性
人们常常认为,如果我们治愈衰老或找到如何上传人类思想,人类就会永生。 今天我们将研究这个概念,看看它与天文时间线的关系如何。
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Jakub Grygier 的封面艺术:https://www.artstation.com/artist/jak…
图形团队:
爱德华·纳德拉.
贾里德·伊格利.
贾斯汀·迪克森。
凯蒂·伯恩。
Mafic Stufios 的 Kris Holland:www.maficstudios.com。
米绍·约尔达诺夫。
皮埃尔·德梅特.
塞尔吉奥·博特罗:https://www.artstation.com/sboterod?f…
斯特凡·布兰丁。
脚本编辑:
安迪·波佩斯库。
康纳·霍根。
爱德华·纳德拉.
尤斯特拉修斯·格雷厄姆.
格雷戈里·莱尔.
杰斐逊·伊格利.
卢卡·德·罗莎.
马克·沃伯顿。
迈克尔·古谢夫斯基。
米奇·阿姆斯特朗。
莫尔博组织。
娜奥米·科恩.
菲利普·鲍尔多克.
西格蒙德·科佩鲁德.
史蒂夫·卡登。
蒂芙尼·彭纳。
音乐:
马库斯·朱尼卡拉,\
来源和详细信息:
https://www.youtube.com/watch?v=6icg0tu_5z4&si=9aWP6IlzbxD42XDZ
端粒长度测试#12:饮食和端粒长度的相关性
加入我们的 Patreon。 https://www.patreon.com/MichaelLustgartenPhDDiscount 链接:端粒、表观遗传测试:https://trudiagnostic.com/?irclickid=U-s3Ii2r7x…
来源和详细信息:
Geoffrey Hinton | Will digital intelligence replace biological intelligence?
Geoffrey Hinton will be presented at the University of Toronto on October 27, 2023 by the Schwartz Reisman Institute for Technology and Society and Department of Computer Science in collaboration with Vector Institute for Artificial intelligence and Cosmic Future at the Faculty of Arts & Science.
Opening remarks and introduction.
0:07:21 — 0:08:43 Overview.
0:08:44 — 0:20:08 Two different ways to do computation.
0:20.09 — 02:30.11 Can large language models understand what they say?
The first neural network language model.
Will we be in a position to control the super-intelligence when it surpasses human intelligence?
0:57:25 — 1:03:18 Does digital intelligence have subjective experience?
1:03:19 — 1:55:36 Q&A
1:55.37 — 1:58.37 Closing remarks
Talk title: \”Will digital intelligence replace biological intelligence?\”
Abstract: Digital computers are designed to let a person tell them what to do. The models can be used on different hardware pieces, even though they require high energy. We could use analog computations that are very low-power and take advantage of the unique properties of hardware to mimic biology in order to create computers that can learn. It is necessary to have a learning algorithm which can use analog properties even without a model. The computation becomes mortal when it uses the analog properties that are idiosynchratic to the hardware. The learned knowledge is lost when the hardware dies. It is possible to transfer the knowledge to a newer analog computer if the latter can mimic the older computer’s outputs. However, this process of education takes a long time. Digital computation allows for many copies of the exact same model to be run on different hardware. By averaging the weight changes of thousands of digital agents, they can share their learnings very efficiently. Chatbots such as GPT-4 or Gemini are able to learn thousands of time more than a single person. Digital computations can also use backpropagation, which is a much more scalable learning method than analog hardware. I believe this leads me to think that digital computation on a large scale is likely better at acquiring information than biological computation, and could soon be more intelligent than we are. Digital intelligences should be less vulnerable to war and religion because they are immortal and have not evolved. However, if one of these digital super-intelligences ever wants to take over, it’s unlikely we can stop them. Therefore, the most pressing question for AI research is to find a way to prevent this from happening.
Geoffrey Hinton
Geoffrey Hinton earned his PhD in artificial Intelligence from Edinburgh University in 1978. He moved from Carnegie Mellon to the Department of Computer Science of the University of Toronto where he now is an Emeritus Professor. Google acquired Hinton’s neural networks startup DNN research in 2013, which was developed from his research at U of T. Hinton then served as a Vice-President and Engineering Fellow for Google until 2023. He is the founder of Vector Institute for Artificial intelligence where he serves as Chief Scientific Advisor.
来源和详细信息:
https://www.youtube.com/watch?v=iHCeAotHZa4&si=8yjSkHNwWEfsd57F
Fermi Paradox – The Impossible Earth Hypothesis
They haven’t been able to contact us because they have either uploaded themselves in digital information, where they can live forever and create simulated worlds or they have uploaded themselves onto femto-tech level computational substrates.
Is Earth possible? The impossible earth hypothesis is explored and the implications for science and existence are discussed.
My Patreon page:
/ johnmichaelgodier.
My Event Horizon Channel
/ eventhorizonshow.
Music:
来源和详细信息:
Eric Topol
https://music.youtube.com/watch?v=n_LefGJgOJ8&si=UoInnL8Xy_wsXv_
Listening to this. He’s decent, right up there with Dr Daniel Amen when it comes to ideas and advancement. This episode was barely begun, but I’m learning that AI is a great tool for medicine. There are also more podcasts in this podcast about our own health. These are some of the key issues to longevity.
Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks https://bit.ly/IncreaseHealthspan.
View the Show Notes For This Episode: https://bit.ly/ep-855
Eric Topol, PhD, is Professor of Molecular Medicine and Executive Vice President of Scripps Research. He founded and directs the Scripps Research Translational Institute. He is a top-ten most-cited researcher in medicine, having published more than 1,200 peer reviewed articles, with over 330,000 citations. His main scientific focus is on individualized medicine, using genomic, digital and AI tools.
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来源和详细信息:
https://music.youtube.com/watch?v=n_LefGJgOJ8&si=UoInnL8Xy_wsXv_-
Reprogramming Cells to Rejuvenate
A recent review in Ageing Research Reviews summarises the research on epigenetic programming and its potential for rejuvenation therapy.
The epigenome changes with age. These changes can affect gene regulation and cellular homeostasis. They can also play a part in age-associated phenotypes. The addition or removal chemical groups from DNA or DNA-associated protein has a profound effect on gene expression, tissues functions and identity.
The authors of this review believe that epigenetic reprogramming is one of the most promising interventions currently available to delay or stop aging. It could even reverse it at the cell level. The authors believe epigenetics is the foundation of aging. Therefore, being able impact the epigenome will allow them to address several Hallmarks of Ageing simultaneously.
来源和详细信息:
ATR prevents telomerase converting DNA breaks to telomeres
ATR kinase signals are able to keep human telomerase in check. Telomerase adds telomeres on broken chromosomes, which threatens genome integrity.
来源和详细信息:
https://www.science.org/doi/10.1126/science.adg3224